This Because Hoodia gordonii is new, there are limited numbers of scientific trials that try to comprehend the effect that this plant can have on the body. I encountered so much difficulty in locating actual clinical trials that I was only able to find one study pertaining to Hoodia gordonii. In fact, only short term studies have been done. While searching for clinical trials in Hoodia gordonii, I was unable to find trials that specifically used the plant. The trials I was able to find isolated the molecule P57 from Hoodia and then ran experiments on it. According to the findings from the study above, Hoodia gordonii or its molecule P57 actually increase the hypothalamic ATP. This means that the energy in the body is increased when Hoodia gordonii is introduced into the body. The increase in energy could be one possible cause of appetite suppression in individuals. While the evidence from MacLean’s study supports the idea that Hoodia gordonii is an appetite suppressant, I still have reservations with the claims made by companies selling this product. One hesitation I have is that I only found a study where rats were the subjects. For me to believe in the power of Hoodia, I would need to see clinical trials with humans as the subjects. Another reservation I have is that I think Hoodia could actually be an appetite suppressant but probably not to the degree that some of the personal testimonials claim. I feel that testimonials are often sensationalized. -480 New York, United States "unique hoodia side effects " and "healthy diet tips to lose weight " (include "what is the best diet supplement", "effective weight loss for women ", "natural appetite suppressant pills ", "incredible weight loss stories ", "healthy fat burning supplements ", "Weight loss clinical studies ", 20 Oct 2005 – Hoodia supplements are marketed and used to reduce appetite and aid weight loss. In fact, the demand has outstripped the supply of hoodia, & Effective natural products )